Police said two mortars struck the area wounding five civilians. One Reuters reporter said vehicles were ablaze. Another said two columns of smoke were visible.
An Iraqi military officer said that one soldier was wounded in the blasts, AFP reported.
The Foreign Ministry building is adjacent to the fortified Green Zone government and diplomatic compound, where journalists were assembled for a news conference for Negroponte and Iraqi Foreign Minister Hoshiyar Zebari.
Militants have fired rockets or mortars at the Green Zone during visits by senior